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Rapid Opioid Detoxification under Anesthesia (RODA)

CALDA Clinic offers a safe, well established and time saving procedure for opioid detoxification under anesthesia.

The CALDA RODA Program initially includes 2-4 days in our partner clinic Privatklinik Bethanien, followed by at least 4 weeks of the CALDA Full Program in one of our CALDA residences.

Costs per person for four weeks: CHF 576,000
Rehabilitation of people addicted to opioids can only begin after an initial period of abstinence. This period is variable and is associated with an extremely unpleasant withdrawal syndrome.

The character and severity of symptoms such as sweating, shivering, nausea, vomiting, diarrhea, abdominal cramping, anxiety, and muscle pain are major deterrents to patients wanting or needing to undergo detoxification. Conventional detoxification methods include tapering doses of a substitute agonist drug, the use of μ-opioid receptor antagonists, and the use of clonidine, which has been used alone and in combination with antagonists to reduce withdrawal symptoms.

These techniques, requiring 3–21 days, are associated with the onset of the withdrawal syndrome described previously and may necessitate admission for inpatient monitoring. Consequently, significant initial dropout rates are seen, ranging from 30-91%.

Recently, a different approach to detoxification from opioids emerged: the administration of a high- dose μ-receptor antagonist during general anesthesia. Well-designed protocols accelerate detoxification and attenuate withdrawal symptoms. The procedure should result in 100% detoxification rates, should be safe, and should be accomplished within one to two days.

The object is to complete a full detoxification and avoiding the possible severe syndromes during withdrawal. By performing a detoxification under anesthesia the patient gains time for the rehabilitation program, knowing that the chance of a set back is lower.

Process of rapid opioid detoxification under anesthesia (RODA)

The process of RODA includes three steps:

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Step 1

Information, patient motivation, psychiatric assessment, informed consent, full medical assessment (including internal check-up: lab results, drug levels, CT/MRI of brain)

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Step 2

Rapid detoxification under anesthesia (Intensive care unit 1-2 days)

  • Patient monitoring: Blood pressure, oxygen saturation, bi- spectral index (BIS)
  • Induction of anesthesia: arterial blood pressure, central venous catheter, bladder catheter etc.
  • Start detoxification with Naloxone (Naloxone hydrochloride)
  • Extubation after test application of Naloxone (approx 15-20h after induction)
  • Post interventional recovery at the ICU for about 12 hours

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Step 3

Recovery: one to two days at the hospital, followed by the CALDA Full Program

  • Continuous intake of Naltrexone p.o.

CALDA Full Program

With the CALDA Full Program, you receive the entire CALDA treatment based on our unique CALDA Concept, which is implemented by our proven successful, international medical team as well as our highly qualified network of experts. We guarantee tailored precision medicine and individual one-to-one premium consulting.


Psychiatric Diagnostics 
In Psychiatric Diagnostics, we ascertain your mental state, your personal as well as social anamnesis (medical history) and your addiction and family anamnesis.

Orthomolecular Diagnostics 
As part of Orthomolecular Diagnostics, we perform an extensive clinical-chemical analysis, which involves the following examinations:
Allergies and intolerances, amino acid status, inflammation, fatty acid profile, heart rate variability (HRV), hormonal balance, bone metabolism, metabolites, microbiome, micronutrient status, food intolerance, neurotransmitter status, oxidative stress, nitrosative stress, stress profile, stool and digestion analysis.

Through the epigenetic analysis, we find out more about the following values:
Breakdown of food components, antioxidative capacity, iron absorption and utilisation, detoxification approach with toxins, fat metabolism-cholesterol, bone metabolism, lactose malabsorption, pharmacogenetics, reaction to inflammations and infections, stress and mood, obesity and diabetes, vitamin levels (B vitamins, homodystein), Coeliac risk.

Based on these comprehensive diagnostics, we are able to offer you a treatment individually tailored to you.


For long-term results, we recommend a minimum stay of four weeks at the CALDA Clinic. A personal coach will live with you 24/7 during the entire period. The therapeutic program comprises six to eight hours a day, seven days a week and is structured as follows:

Psychiatry and Psychotherapy

  • Intensive psychotherapy (CBT, EMDR, clinical hypnosis)
  • Resource activation
  • Self-management
  • Mood stabilisation
  • Disorder-specific psychoeducation
  • Stress management

Orthomolecular Medicine

  • Amino acids, minerals and vitamins from the first day
  • Personalised CALDA micronutrient mixture for three to six months
  • Personalised lifestyle coaching
  • Personalised diet coaching
  • Personalised meal preparation

Alternative and Complementary Medicine
Aside from classic conventional medicine, there are a range of traditional medicinal and therapy worlds. As an advocate of integrative medicine, we have expanded our range of measures with proven and successful formulas from alternative and complementary medicine. We tailor our weekly program to you. The most successfully implemented treatment elements are the following:

Acupressure, acupuncture, breathing/singing and voice therapy, ayurveda, physiotherapy, chronotherapy, coaching through the 12-step program, cranial electrotherapy stimulation (CES), art and creative therapy, manual therapies, meditation and mindfulness, neurofeedback, personal training, equine-assisted psychotherapy, phytotherapy, tango therapy, yoga.

In our luxurious and private residences, you can switch off in peace, recuperate and be treated. A premium full service with butler, chef and luxury limousine service with chauffeur is included.

You can find further information on the CALDA Residences here.

External hotel costs, medical services by third-party institutes and post-treatment programs are not included.


We charge you CHF 576,000 per person for the CALDA RODA Program for four weeks.

External hotel costs, medical services by third-party institutes and post-treatment programs are not included.

Should you have any questions or uncertainty, we will be happy to help you at any time.